Description

PhenoFiler™ is a novel platform which combines high throughput target profiling with proprietary bioinformatics analysis and with high-content siRNA knockdown phenotypic screening in cell cultures.

Application

• Target Identification: Revisit known targets or identify novel ones
• Target Prioritization: Use the latest in silico methods to sift through potential targets and select those with the greatest chance of success
• Target Validation: High throughput functional and high-content screening

Platform

• mRNA Expression Profiling: Availability of multiple platforms enabling the identification of targets on a genome-wide, customized or individual gene scale
• ReLyter™: Proprietary software tool for identification of functional relationships between novel and known genes, ability to combine in-house and public datasets for further analysis
• siRNA Knockdown: High throughput assay development of si- and shRNAs, primary and established cell cultures, high-content screening (e.g. apoptosis, proliferation, toxicity, etc...)

Use Geneservice because...

• Quality: We are committed to a high quality service that helps ensure reproducibility and accuracy of the results
• Outsourcing Service: Geneservice is an ISO certified premier supplier of contract research with a proven quality record
• Experience: Over 10 years of experience in genomics, running a national core laboratory in the UK.
• Turnaround time: Turnaround time is typically from 6 to 8 weeks, depending on the scale of the service you require
• Exclusive: Access to the ReLyter™ software and the HTP RNAi screening platform

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