aCGH Resources

As part of the Medical Solutions group, Geneservice are delighted to announce the distribution of high quality BAC arrayed slides for array Comparative Genomic Hybridization (aCGH). aCGH utilizes discrete segments of DNA as immobilized targets to assess relative DNA copy number changes between two different fluorescently labelled DNA samples:

Human ACCUArray™ is a whole-genome, human male 19k RPCI-11 BAC array with 160kb resolution. The BAC clones are spotted in duplicate on the arrays for quality purposes and statistical replication. The arrays are perfect for the quick determination of amplifications, deletions and abnormalities in the genome. The resolution allows for copy number determinations observed most frequently in cancer as well as syndromes associated with aneuploidy.

Mouse ACCUArray™ is great tool for accessing copy number aberrations in the mouse genome, by utilising 6,500 RPCI-23 and RPCI-24 BAC representations as targets. The 0.5mb resolution allows for copy number determinations observed most frequently in mouse models of cancer as well as an efficient means to determine ES cell genome stability.

If you have any specific requirements, or would like further information, please contact biohelp