News
22 Jun 2009: You’ve Heard the Whispers – We’re Silencing MORE Genes
Human shRNAi Library
To complement Geneservice’s™ expanding portfolio of resources, we are delighted to offer a short-hairpin RNA (shRNA) library constructed by the ‘The Netherlands Cancer Institute (NKI). This library has been specifically tailored for applications in mammalian cancer genetics.
This library has substantial advantages over other similar resources including full sequence verification and knockdown validation.
This library consists of 13,500 clones which target approximately 5000 cancer related genes. We offer an accompanying easy gene symbol search tool for the library with up to three 19-mer target sequence constructs found per gene. This library also offers a unique barcode system to expedite screening in high-throughput experiments.
Any Questions? Contact:
Dr Andy Walker
01223 432 607
29 Apr 2009: Human Domain Antibody Library: Same Complexity - Reduced Aggregation
Human Domain Antibody Library
GeneserviceTM is pleased to announce the availability of the Domain Antibody Phagemid library constructed by Dr Daniel Christ(formally of the MRC Laboratory of Molecular Biology, Cambridge UK and currently based at the Garvan Institute, Sydney, Australia).
This library offers significant advantages over the hugely successful Tomlinson I + J library introduced by us in 2002, benefiting from greatly reduced aggregation with no loss of complexity.
This artificial library of antibodies can be used to derive binders to almost any target molecule using phage display and selection. These binders can be used for the same applications as conventional monoclonal antibodies (ELISA, Western blotting, FACS, immunohistochemistry), but can be isolated in a fraction of the time and without the need for animal immunisation.
Phage-antibody libraries have been used successfully in hundreds of molecular biology labs worldwide to derive highly specific antibody reagents to a wide range of different proteins, peptides or small molecule compounds. We are pleased to continue to offer our customers high quality, innovative products at a competitive price.
Contact:
Dr Andy Walker
info@geneservice.co.uk
Tel: 01223 432 607
17 Sep 2008: StarGate®: The next dimension of combinatorial cloning has arrived! Multiple sites for multiple insertions, minimal gene modification
StarGate®
The next dimension of combinatorial cloning has arrived…….
Fasten your seat belts and prepare for take off with the
StarGate® Cloning System
StarGate® will save you time and reduce the frustrations often associated with complex cloning. StarGate® offers a huge range of acceptor vectors to choose from and each vector has unique attributes to aid in the expression of your gene of interest.
Major Benefits of StarGate®
Ordering Information
v Introductory 50% discount on the ‘Newcomers’ kit
v Multi-buy acceptor vector discount: buy 8 get 50% off the single vector price
Dr Andy Walker Commercial Development Manager commented, “The StarGate® kit, in conjunction with the millions of clones distributed by Geneservice, gives the researcher an excellent opportunity to plan and order all of the components required for their expression analysis experiments.”
11 Feb 2008: Medical Solutions enters an exclusive UK agreement with Empire Genomics LLC as a distributor and service provider for ACCUArray genotyping
Medical Solutions enters an exclusive UK agreement with Empire Genomics, LLC as a distributor and service provider for ACCUArray genotyping
The Board of Medical Solutions plc (LSE: MLS), the provider of expert, quality DNA sequencing and genotyping services to the healthcare, pharma biotech and life sciences research sectors, is pleased to announce that it will partner with Empire Genomics, Inc. to be the exclusive UK distributor and service provider for its ACCUArray array comparative genomic hybridization (“aCGH”) genotyping technology.
In addition to distributing the product, Medical Solutions will also offer the genotyping service from its laboratories in Nottingham, which will include in-house bioinformatics analysis and support.
HIGHLIGHTS
- Exclusive distributor and service provider in the UK;
- Medical Solutions to offer both Human and Mouse ACCUArray aCGH as a product and also provide the genotyping service that will include in-house bioinformatic analysis;
- Novel DNA array for pre-natal, cancer and pharmacogenetic testing with diagnostic and research applications;
- Enhanced portfolio of genomic products and services provided in GLP, GCP and CPA accredited laboratories.
The addition of Empire Genomics ACCUArray will complement Medical Solutions existing portfolio of genomic products and contract research services including DNA clones and genomic analyses. The assay has clinical diagnostic applications for the healthcare community and can be used for pharmacogenetic testing by companies in the pharma biotech sector. This further demonstrates the Company’s commitment to be a market leader in the UK for the provision of expert, quality laboratory services and genomic reagents to the healthcare and life science research sectors.
Dr Tom Weaver, Commercial Director for Medical Solutions, said “The diagnostic capability of this assay is of particular interest to those groups in the healthcare community involved in cytogenetic and pre and post natal testing. ACCUArray aCGH provides a tremendous tool for the identification of genetic aberrations linked with a number of diseases and conditions such as cancer, autism, mental health problems including Alzheimer’s, several congenital abnormalities and certain syndromes including Down Syndrome”.
Dr Weaver added “The Empire Genomics aCGH kit, provides a high resolution and robust screening procedure for researchers, clinicians and pharmacologists. The supporting software provides data analysis within 24 hours in a concise and accessible format.”
Contact:
Dr. Andy Walker
Commercial Development Manager
Tel: 01223 432 607
andy.walker@medical-solutions.co.uk
04 Feb 2008: First UK commercial service provider of Illumina next generation DNA sequencing and genotyping applications
Medical Solutions becomes first UK commercial service provider of Illumina next generation DNA sequencing and genotyping applications
The Board of Medical Solutions plc (LSE: MLS), a UK-based provider of expert, quality DNA sequencing and genotyping services to the healthcare, pharma biotech and life sciences research sectors, is pleased to announce that it is implementing a new technology platform at its Nottingham laboratory that will help to broaden the Company’s offering and increase efficiencies.
Medical Solutions will become the UK’s first commercial service provider for these leading edge systems, which it will be sourcing fromIllumina, Inc.
HIGHLIGHTS
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Complete pipeline of histopathology to genomic services, including DNA extraction, biobanking, whole genome amplification and DNA sequencing in GLP, GCP and CPA accredited laboratories
Adoption of Illumina’s DNA sequencing and genotyping platforms will complement Medical Solutions’ extensive portfolio of diagnostic and contract research services ranging from cell and tissue to genomic analysis. This further demonstrates the Company’s commitment to be a market leader in the UK for the provision of expert, quality laboratory services to the healthcare, pharma biotech and life science research sectors.
Dr Tom Weaver, Commercial Director for Medical Solutions said, "We selected the Illumina platforms because the data quality, reproducibility, flexibility and breadth of applications are, in our opinion, the best in the industry. This represents cutting edge technology capable of revealing an enormous volume of genetic information. Customers have already expressed significant interest in applications run on the Genome Analyzer and BeadStation platforms, and it is our intention to develop strategic partnerships with these early adopters, enabling them to take full advantage of the power of whole genome analysis by providing high-quality data in an accredited quality laboratory environment. "
Dr. Weaver added, “Illumina DNA sequencing and genotyping platforms are also capable of delivering analyses in the expanding field of personalised genomic services.”
“The addition of Illumina’s Genome Analyzer and BeadStation platforms demonstrates the level of commitment Medical Solutions has to its customers and to providing them with leading-edge technologies that enable whole genome analysis” said Karen Possemato, Director of Corporate Marketing at Illumina. “Their added interest in becoming an Illumina CSPro further supports the value Medical Solutions sees in Illumina’s products and how this program can be a key factor in their success.”
Contact:
Dr. Cheng Eng Ang
Commercial Manager
Tel: 01223 432 608
Mob: 07919 341 172
cheng-eng.ang@medical-solutions.co.uk
08 Jan 2008: Invitation to attend Medical Solutions Nottingham laboratory open day on 22nd January 2008
Medical Solutions plc
Invitation to attend contract research services laboratory open day
Nottingham
22 January 2008
Tour of state of the art laboratories at 11.00am and 4.00pm
Lunch & refreshments available
Medical Solutions, a leading provider of expert, quality services and products to the Healthcare, Pharma Biotech and Life Science Research sectors, will be holding an Open Day at its newly commissioned contract research services laboratory in Nottingham on 22 January 2008. There will also be an opportunity to view our state of the art reference laboratory facilities.
This Open Day provides an ideal opportunity to inform our customers, academic and research institutions of the full range of services and expertise offered by the Company and we very much hope it is an invitation you will be interested in accepting.
It is planned to have two tours of the laboratories, at 11am and 4pm, at which key laboratory managers and staff will be on hand to answer any questions you may have. Each tour will be preceded by a short presentation delivered by senior management, covering key activities including:
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DNA sequencing, genotyping and gene expression analysis
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Molecular pathology including FISH, HPV, KRAS, OncotypeDX™ and other diagnostic assays
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Automated imaging and digital image capture and analysis
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Biobanking (DNA and tissue) and clinical trials
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Histopathology and cytology
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Immunohistochemistry and antibody cross reactivity
Refreshments will be available after both lab tours, providing a further opportunity to network with senior management and technical personnel.
May I ask that you respond to this email by Thursday 17th January, indicating whether or not you will be attending and which session would be your preference (morning or afternoon). The following link gives directions to our location at Nottingham Business Park http://www.medical-solutions.co.uk/directions.aspx, where there is ample car parking.
To book your place on a tour, or for further details, please contact Stephanie McHugh on 01223 432 620 or Stephanie.mchugh@medical-solutions.co.uk. We very much hope that we will have the pleasure of welcoming you to Medical Solutions on the 22nd January.
Kind regards
Stephanie McHugh
Marketing Specialist
Tel: 01223 432620
Medical Solutions plc
1, Orchard Place
Nottingham Business Park
Nottingham
NG8 6PX
22 Nov 2007: Medical Solutions Geneservice Mini Exhibitions - New Dates Added
Medical Solutions Geneservice, provider of genomic products and contract research services, will be holding a series of mini exhibitions designed to inform the research community how the Company can help in the areas of:
• DNA Sequencing (free trials available)
• Gene expression analysis
• Genotyping
• Whole Genome Amplification
• cDNA/genomic/miRNA clones and libraries
Planned dates and venues:
v Friday 23rd November
10am – 2pm
School of Biosciences, University of Birmingham
v Tuesday 27th November
10am – 2pm
School of Biosciences, University of Nottingham
v Thursday 29th November
10am – 2pm
School of Biomedical Sciences, University of Nottingham
Please do come along and talk to us about your requirements
Contact
Marketing Specialist
Milton Road,
Cambridge.
CB4 0FE
Email: smchugh@geneservice.co.uk
29 Oct 2007: Medical Solutions Geneservice Mini Exhibitions
Medical Solutions Geneservice, provider of genomic products and contract research services, will be holding a series of mini exhibitions designed to inform the research community how the Company can help in the areas of:
• DNA Sequencing (free trials available)
• Gene expression analysis
• Genotyping
• Whole Genome Amplification
• cDNA/genomic/miRNA clones and libraries
Planned dates and venues:
v Tuesday 30 October
10am – 2pm
Harwell Medical Research Council
v Wednesday 31 October
10am – 2pm
Cambridge Institute for Medical Research
v Tuesday 6 November
10am – 2pm
Rayne Building, London
v Thursday 8 November
10am – 2pm
Laboratory of Molecular Biology (LMB), Cambridge
v Wednesday 21 November
10am – 2pm
Wellcome Trust Centre for Human Genetics, Oxford
v Thursday 6 December
10am – 2pm
Department of Biochemistry, Bristol University
v Thursday 13 December
10am – 2pm
Royal Veterinary College, Hawkshead
Please do come along and talk to us about your requirements
Contact
Marketing Specialist
Milton Road,
Cambridge.
CB4 0FE
Email: smchugh@geneservice.co.uk
05 Oct 2007: Medical Solutions Extends Partnership with Oxford University and Achieves Extended ISO 9001:2000 Certification
Medical Solutions is pleased to see the expansion of it’s DNA sequencing activities through an extended partnership with the University of Oxford. The DNA sequencing facility previously run by the Department of Pathology has been incorporated into Medical Solutions’ Oxford DNA sequencing laboratory, the second core laboratory to join forces with Medical Solutions since January. The company now has the largest commercial sequencing capability in both Cambridge and Oxford and looks forward to continued growth through similar partnering opportunities.
In addition to this, the sequencing laboratory at Oxford University has received the International Standards Organisation's (ISO) 9001:2000 certification for the provision of functional genomic products and contract research to academic and commercial research communities worldwide and to sequencing/contract research in satellite laboratories in the UK. This follows external validation by Lloyds Register of Quality Assurance (LRQA) a United Kingdom Accreditation Service (UKAS) accredited quality certification body. ISO 9001 is an internationally recognised standard that represents good management practices and aims to ensure that organisations consistently deliver the products or services that meet their clients’ quality requirements. The achievement of ISO 9001:2000 approval reinforces Medical Solutions’ continued commitment to identify and meet the needs and expectations of its customers and achieve, maintain and improve overall operational performance and capabilities
Nick Leaves commented:
"This partnership and certification demonstrates Medical Solutions’ constant determination and commitment to providing elite levels of both product and service quality. We are dedicated to being the premier supplier of genomic products and technical services to our customers."
Contact
20 Aug 2007: Medical Solutions Geneservice chosen to be Applied Biosystems’ UK service provider for SNPlex™ Genotyping System
The Board of Medical Solutions plc (LSE: MLS), the diagnostics and healthcare business, is pleased to announce that its recently acquired genomic services and products business Geneservice Limited has been chosen by Applied Biosystems to be the UK service provider of its SNPlex™ Genotyping System and help broaden access to its genotyping technology. Applied Biosystems is headquartered in Foster City, California, and reported sales of over US$1.9 billion during 2006.
HIGHLIGHTS
- Geneservice to benefit from marketing and technical support;
- Geneservice was selected because of its proven proficiency in executing the SNPlex™ chemistry workflow and
- SNPlex™ platform will enhance Geneservices’ delivery of advanced genotyping services.
As part of Applied Biosystems’ SNPlex™ Service Provider Program, Geneservice will benefit from marketing and technical support - which is expected to enhance its ability to deliver advanced genotyping services to its clients. Geneservice was selected because of its proven proficiency in executing the SNPlex™ chemistry workflow and generating reliable data using GeneMapper™ software for data analysis.
Geneservice will use the Applied Biosystems’ SNPlex™ technology and genotyping and sequencing platforms to offer a system for projects needing to genotype multiple single nucleotide polymorphisms (“SNPs”) from hundreds or thousands of samples.
The SNPlex™ Service Provider Program is intended to enable researchers who do not have access to capillary electrophoresis (“CE”) genetic analysis instrumentation to obtain a flexible and bespoke high-throughput SNP genotyping data solution.
Nick Leaves, Head of Operations for Medical Solutions said: "The SNPlex™ Genotyping System is well suited to the candidate gene association studies that typically follow whole-genome screening. We already have significant expressions of interest in SNPlex™ and have completed over 900,000 custom SNP genotypes in recent months. We are delighted to have had our experience recognised by Applied Biosystems and to have been chosen as its partner for this technology in the UK.”
Contact:
Nick Leaves
Head of Operations
Medical Solutions plc
1 Orchard Place
Nottingham Business Park
Nottingham
NG8 6PX
Tel: +44 (0) 115 973 9012
Fax: +44 (0) 115 973 9013
www.medical-solutions.co.uk
03 Jul 2007: Acquisition by Medical Solutions plc
The Board of Medical Solutions plc (LSE: MLS), the diagnostics and healthcare business specialising in histopathology and cytology services and products, announces that at its Extraordinary General Meeting held today shareholders passed unanimously the resolution for the acquisition of Geneservice Limited.
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